Home Journals IJTER Archives Vol. 1, No. 3 Acoustic studies of cefotaxime sodium in aqueous medium at d...

International Journal of Technology and Emerging Research

e-ISSN: 3068-109X p-ISSN: 3068-1995 DOI: 10.64823/ijter Current Volume: 2 — Issue 8 (August 2026) (2026)
Article Info
Open Access Research Article
12 pages PDF

Acoustic studies of cefotaxime sodium in aqueous medium at different temperatures and at frequency 5 MHz under atmospheric pressure

by ,

International Journal of Technology and Emerging Research 2025 , 1 (3) , 262–273

10.64823/ijter.2503031
Received: 28 Jul 2025 Published: 29 Jul 2025
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Abstract

Ultrasonic velocity (U) and density (ρ) measurements have been performed for the antibiotic Cefotaxime Sodium in aqueous solution at five temperatures: 20°C, 25°C, 30°C, 35°C, and 40°C. These experimental values were employed to compute several thermodynamic and acoustic parameters, including adiabatic compressibility (βₐ), change in adiabatic compressibility (Δβ), relative adiabatic compressibility (Δβ/β°), apparent molal volume (Φᵥ), apparent molal compressibility (Φₖ), and their respective limiting values, Φ°ᵥ and Φ°ₖ. The variation of these parameters with temperature and concentration was analyzed to explore the structure-making or structure-breaking behavior of Cefotaxime Sodium in aqueous medium. The findings provide valuable insights into solute–solvent interactions and the molecular characteristics of this β-lactam antibiotic under thermal perturbation.

Keywords: Ultrasonic velocity, Interferometer, Cefotaxime Sodium, adiabatic compressibility, apparent molal volume, Aqueous medium.

© 2025 The Author(s). Published by IORO Publications. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, distribution, and reproduction in any medium, provided the original author and source are credited, a link to the license is provided, and any changes are indicated.

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